Elevated phosphorylation and aggregation of Tau are widely considered pathological hallmarks in Alzheimer's disease (AD) and other tauopathies
Anti-Siglec-8 antibody administration in vivo to humanized and transgenic mice selectively expressing Siglec-8 on mouse eosinophils and mast cells confirmed the in vitro findings
Test Range 312
By interacting with the TCR (T cell receptor) and MHC I molecules
Other biological fluids: Centrifuge at 1000×g for 20 minutes
PAX8 Recombinant Rabbit mAb, PBS Only (SDT-R509) Apoptosis Detection Elevated phosphorylation and aggregation ofProduct Specification Host Rabbit Antigen PAX8 Synonyms Paired box protein Pax 8 Location Nucleus Accession Q06710 Clone Number SDT R509 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF, ICFCM, ChIP Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution, 4C as supplied Dilution